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Side effects are uncommon and have not been clearly defined
ROS can produce 50,000200,000 AP sites in the genome of a mammalian cell every day, and it is estimated to produce significantly more AP sites in the brain (Atamna et al., 2000)

Nature 486:54953 [DOI] [PMC free article] [PubMed] [Google Scholar] 153.Munn DH, Bronte V

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In the last analysis they have returned to normal, as they had been for years