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453 Indeed, GLP-1RAs, including exenatide, liraglutide, and semaglutide, have been linked to the diminished expression of matrix metalloproteinases (MMPs)

Mice heart tissues were homogenized with 200 L of water

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The cells were then fixed in 4% paraformaldehyde with 0.2% glutaraldehyde (electron microscopy grade) in HEPES-buffered saline, containing 30 mM HEPES (pH 7.5), 100 mM NaCl and 2 mM CaCl 2 for 20 min

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Canadian Journal of Neurological Sciences