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Over time, the constant excretion of cortisol begins to fatigue the adrenal glands, and because the adrenals produce reserve stores of sex hormones, such as estrogen, progesterone, and testosterone, it may cause the body to steal the materials needed to make these sex hormones and convert them into more cortisol

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The dose escalation period represents the most challenging phase, and strategic timing of supportive peptides can ease this transition
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Arafa MA, Waly MI, Jriesat S, Khafajei AA, Sallam S (2011) Dietary and lifestyle characteristics of colorectal cancer in Jordan: a case-control study