glutathione peroxidase antioxidant 2 - an overview Interplay of antioxidants in Alzheimer's
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& Lehmann, R

These are commonly referred to as ROS

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Pierrel echoes this, adding that estrogen has antioxidant properties of its own, but as estrogen levels drop during perimenopause and menopause, oxidative stress rises

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Mechanistically, ox-LDL induces lipid peroxidation by inhibiting the SREBP-1/SCD1/FADS2-mediated lipid biosynthesis pathway, leading to endothelial damage and ultimately inducing ferroptosis ( 3.3 Ferroptosis and the inflammatory response The discovery of ferroptosis may explain iron accumulation's biological effects
