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Mutations of KRAS (32%) and p53 (46%) are two of the most common gene mutations in LUAD and the co-occurrence of these two gene mutations is frequently observed [99]

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To this end, the development of new therapies, ideally targeting synovitis and inflammatory-related bone erosion in joints, as well as regulating those inflammation-independent factors that can also interfere with bone homeostasis in RA, such as the general RANKL signaling pathway, would be promising for remodeling bone homeostasis in RA

It seems that supervised ML models, such as those based on logistic regression, decision trees, and neural networks, could optimize the process of assessment and quantification of OS [141]

Treating that lump is simpler than you might think