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In the face of foam cell buildup and excessive cell death, efferocytes can become overwhelmed, leading to the loss of atheroprotective effector functions, cell death, and the release of pro-inflammatory DAMPs, which all augment the proatherogenic environment 2

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J., et al., Lisdexamfetamine Dimesylate in Binge Eating Disorder: A Placebo Controlled Trial, Human Psychopharmacology 31 (2016): 382391