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Senescent cells upregulate FOXO4 expression to sequester p53 in the nucleus, preventing it from initiating the mitochondrial apoptosis pathway

Research has shown that the absence of GSTP1 promoter methylation expression in prostate cancer is associated with a sensitivity of 73%, specificity of 100%, positive predictive value of 100%, and negative predictive value of 78% (Miyake et al., 2012)

[DOI] [PubMed] [Google Scholar] 63.Bruton JD, Place N, Yamada T, Silva JP, Andrade FH, Dahlstedt AJ, Zhang SJ, Katz A, Larsson NG, Westerblad H

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10.1002/cbdv.201900434 82 YandrapuH.SarosiekJ

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