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Indian J Anim Sci (2010) 80:7278
Free iron in the intestines is reduced from the ferric (Fe 3+ ) to the ferrous (Fe 2+ ) state primarily on the luminal surface (apical membrane) of intestinal enterocytes and then transported into the cell (see Figure below)
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In a meta-analysis of 7 RCTs and 7 retrospective studies ( n = 751 patients), vit-C supplementation showed a significant alleviation in inflammatory response by increasing ferritin levels and lymphocyte counts in COVID-19 721
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These optimization measures are important for improving the stability of ACNs and maintaining their functional properties
