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Medicines in the GLP-1 receptor agonist class, including semaglutide, have been associated with pancreatitis and gallbladder problems
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doi: 10.1038/nrmicro2836 16
Nevertheless, laquinimod did not present a significant treatment effect when administered for PPMS in the ARPEGGIO study (129)
A significant improvement in basal and maximal mitochondrial respiration in vitro was also observed, suggesting a potential approach for treating AD-related mitochondrial dysfunction via intranasal delivery (Wong and Ho, 2018)
