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Accordingly, this system could be developed for various clinical applications, including the treatment of familial short stature, cancer cachexia, eating disorders, and sarcopenia (Kojima and Kangawa, 2005)

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Elevated intracellular calcium concentrations, in turn, appear to prompt the secretory vesicles inside these cells to release growth hormone into the bloodstream

Hence, intracellular Ca2+ mediates both mechanisms of ALAs apoptotic effects [86]

B-cell receptor: from resting state to activate
