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In the brain, the key serotonin hub is the raphe nucleus, but other regions, such as the linear caudal nucleus, oral nucleus pontis centralis, and the postrema region, produce 5-hydroxytryptamine (5-HT)

Lundstrm et al., 2011

10.3844/ajbbsp.2008.85.94 131 RoseS.NiyazovD

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Too much supplementation at high doses can cause gastrointestinal symptoms like nausea, vomiting, cramping or diarrhea, or a fishy body odour

Therefore, the sulfuranyl free radical on the S-atom of Met35 could be formed by molecular oxygen interaction with the S-atom of Met35, leading to an electron transfer to oxygen from the S-atom resulting in the reduction of oxygen to superoxide free radical and the one-electron oxidation of the S-atom to the sulfuranyl free radical and/or ii ) Cu 2+ weakly bound to the S-atom of Met35 conceivably would lead to a one-electron reduction of Cu 2+ and oxidation of the S-atom to the sulfuranyl free radical as discussed above