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Bleaching occurs at first, followed by hyperpigmentation with papules over the treated areas

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Women with HDP exhibited higher levels of copeptin, a pro-segment of arginine vasopressin (AVP) (246), raising the hypothesis that high AVP levels during pregnancy play a role in the pathogenesis of HDP

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[DOI] [PubMed] [Google Scholar] Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shaded E, Levine M
