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According to research published in the International Journal of Molecular Sciences (Pickart et al., 2015), plasma levels drop from about 200 ng/ml at age 20 to approximately 80 ng/ml by age 60

10.1093/jexbot/53.366.1 J

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Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study