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Intranasal and Localized Delivery : Localized routes such as the Minimally Invasive Nasal Depot (MIND) can bypass the BBB by delivering antibodies directly to the olfactory region for sustained brain release

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Alteration of KEAP1-NRF2 activity in ALS The human brain is an organ with elevated demand of energy, relying on oxidative metabolism and high consumption of O 2 to perform its functions [68]

J Hear Sci 10(2):919 Someya S, Kim M-J (2021) Cochlear detoxification: Role of alpha class glutathione transferases in protection against oxidative lipid damage, ototoxicity, and cochlear aging

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