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Description
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Huntington disease (HD) is a neurodegenerative disease caused by a polyglutamine expansion (polyQ) in the Huntingtin protein (muHTT), which makes it prone to misfolding and aggregation
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A Parents Guide to Childhood Cancer: Supporting Your Child with Integrative Therapies Based on a Metabolic Approach

Its molecular network involves CHOP-mediated apoptotic imbalance, NLRP3 inflammasome-activated pyroptosis, the ATF4CHAC1 axis-driven ferroptosis, and the dual roles of autophagy (protective or pro-death)

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