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Vascular EDS (vEDS) is caused by pathogenic variants in COL3A1 , 3 which encodes the pro-1 chain of type III collagen (OMIM 130050) and occasionally specific COL1A1 variants may lead to a vEDS phenotype

Front Immunol 2018;9:1853

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This involves isolating immune cells with high mutational loads and specifically inhibiting this pathway to assess its contribution to the IFN signature and T cell exhaustion

Amycretin: A New Oral Weight Management Drug Amycretin, an oral GLP-1 and amylin agonist, has shown an impressive average of 13% weight loss in phase 1 trials

If you have osteoarthritis or joint pain that keeps you from being as active as you would like, contact me to schedule an appointment with me in South Manchester or Cheshire