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doi:10.1111/j.17457599.2006.00160.x Yang WH, Drouin MA, Herbert M, Mao Y, Karsh J

Cisplatin neurotoxicity - the relationship between dosage, time, and platinum concentration in neurologic tissues, and morphological evidence of toxicity

Changes in the intracellular redox environment of cells, through oxygen-derived free radical production known as oxidative stress, have been reported to be critical for cellular immune dysfunction, activation of apoptotic enzymes and apoptosis

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Materials and methods Animals, treatment, genotyping Female Sprague-Dawley rats with their litter were obtained from Janvier (Genest-Saint-Isle, France)