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This hypothesized VEGF/VEGFR interaction may activate a complex intracellular signaling cascade, which may involve multiple proteins such as phospholipase C, protein kinase C, and the mitogen-activated protein kinases

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Further, NICE and the BNF says that if there are neurological symptoms present, then every other day injections are the recommended treatment, so all the points you make about B12 being stored and sufficient are not really relevant

From here, you can see how Andean condors soar over the abyss, riding the air currents

If you experience any signs of an allergic reaction - such as a rash, unusual itching, or swelling of your face, tongue or throat - seek emergency care right away