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Lastly, research has shown that utilizing an M2-targeting peptide-modified liposome carrier for YY1-targeted therapy in M2 macrophages is highly effective in inhibiting PCa cell lung metastasis and exhibits synergistic antitumor effects when combined with PD-1 blockade (Tsang et al., 2020)

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PBMCs were separated by layering the blood samples diluted twofold in PBS (cat

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1 (2021): 117, 10.1186/S40364-021-00325-5
