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doi: 10.1186/1744-8069-7-6
Current studies are limited to animal models and small numbers of clinical samples, and GPX3 expression can be influenced by medications, diet and lifestyle
The white boxes indicate substrate values (M) and the blue boxes indicate velocities (M/hr)
Nevertheless, our findings demonstrate that cartilage-specific deletion of Igf1 exerts protective effects in two mouse models of osteoarthritis, indicating the important contributing role of cartilage-produced IGF1 in Wnt-triggered joint disease
