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626 However, research on the relationship between HD and ferroptosis is still limited

doi:10.1007/s11095-013-1007-6 [PMC Full Text] [PubMed] [Crosslink] 58

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GSH dysregulation might cause global immune cell autophagy decline with increased generation of proinflammatory cytokines in aging, further provoked by mitochondrial ROS signaling (293)
Pathogenic infections are another trigger of oxidative stress and inflammation for the purpose of immune signaling and eradicating the invadersa process that, while essential for controlling infection, can lead to tissue damage and disease due to heightened oxidative and inflammatory activity

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