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Description
Alpha arbutin is widely available in over-the-counter skincare products and can be safely incorporated into daily routines

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326 Importantly, depletion of SOD2 increases mortality, stroke volume, brain edema and cytochrome C-mediated neuronal apoptosis following transient and permanent middle cerebral artery occlusion (MCAO)

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None of the three compounds have human safety data in pregnancy or breastfeeding, and they are not FDA-approved
