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Nuclear NAD + is generated by nuclear NMNAT1 and is largely utilized by PARPs for DNA damage response and nuclear sirtuins such as SIRT1, SIRT6 or SIRT7 for epigenetic deacetylation 82,86
10.1210/en.2004-0305 Endocrinology 71 PenkeZ.FelszeghyK.FernetteB.SageD.NyakasC.BurletA
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