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We therefore incubated control and ADA2-deficient cells with inhibitors of apoptosis (Z-VAD, pan-caspase inhibitor), necroptosis (necrostatin-1s, inhibitor of RIPK1) and pyroptosis (Z-YVAD, inhibitor of caspase-1) (Fig
Izukawa T, Nakajima M, Fujiwara R, Yamanaka H, Fukami T, Takamiya M, Aoki Y, Ikushiro S, Sakaki T, Yokoi T: Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers

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Apoptotic signaling, another important determinant of muscle integrity under toxic stress, was also evaluated

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