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An acylation cycle regulates localization and activity of palmitoylated RAS isoforms

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Drug repurposing, utilizing various degrees of pre-existing clinical efforts covering efficacy and safety efforts, offsets the high cost and lengthy timeline of de novo drug discovery 231

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Statistical analysis was performed using one-way analysis variance (ANOVA) followed by TukeyKramer post hoc test

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T.WincklerC.WallenbeckA.SpenglerA.KnierimU.KargoM.et al (2018)

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In line with the energy starvation hypothesis [30], which induced that energy supply scarcity was responsible for the contractile dysfunction in heart failure

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