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Normal levels of Ca 2+ in the matrix play various physiological roles, such as the interaction of Ca 2+ with cyclophilin D and ANT to form the mitochondrial permeability transition pore (mPTP)
In particular, AD is closely related to the pathological changes of nerve cells that manifest and persist across the human lifetime
Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, et al
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