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Meta-analysis of homocysteine-related factors on the risk of colorectal cancer

What we know In randomized controlled trials conducted in nonpregnant individuals, low-dose riboflavin supplementation (1.6 mg/day) may lower blood pressure in individuals with a genetic mutation in MTHFR, an enzyme involved in folate metabolism

Decitabine induces responses in patients with myelodysplastic syndrome after failure of azacitidine therapy

10.1016/j.psychres.2024.115992 262 LeeS.-H.ParkS.-Y.ChoiC

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In addition, effective dose and route of delivery are not consistent across studies and because there are no uniform preparations, it makes it difficult to replicate and optimize the dose given