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Drug Interactions of Clinical Significance This article focuses on drug interactions involving specific drugs and drug classes of clinical significance in dermatology, including MTX, cyclosporine A, terbinafine, pimozide, azole antifungals, macrolide antibiotics, quinolone antibiotics, and rifampin (see also Table 1 )

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This is why research suggests that an optimal combination of the three vitamins, B1, B6 and B12, is more effective at relieving nerve damage symptoms and restoring nerve function than taking a single vitamin supplement

They are not interchangeable unless specifically indicated by research protocols