glutathione brain region in Disorders and Aging The role of glutathione peroxidase
Description
& Kopka, K
ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades ( Microglia, the resident immune cells of the CNS, are tightly regulated under physiological conditions to maintain neural homeostasis
Long-term human safety data simply does not exist in published form
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