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Science 351 , 4348 (2016)

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The aim of this review is to clarify biochemical mechanisms related to nutrition and physiological aspects of muscle metabolism related to exercise in order to propose new theoretical bases of treatment which, if properly tested and validated by future trials, could be applied to improve the quality of life of these patients

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It does so by binding primarily to MC-1R and MC-4R, and has lesser effects in MC-3R, three of the five melanocortin receptors in the body

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Curr Opin Rheumatol

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This is because trimethylaminuria often goes unrecognized even by healthcare professionals, and people with mild symptoms dont always seek medical help

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