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Multifaceted actions of melanin-concentrating hormone on mammalian energy homeostasis
T., Kuo W
Bone , 24 3, 195-202
A landmark analysis revealed that while approximately 86% of animal studies with positive findings proceed to human trials, fewer than 5% of those interventions achieve regulatory approval [568]
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4.2 NLRP3 inflammasome in hearing loss Mitochondria ROS has been confirmed as the crucial mechanism of ototoxic drugs
