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Association between Thyroid Autoantibodies and Miscarriage and Preterm Birth: Meta-Analysis of Evidence

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Biochem J 324 (Part 1): 2528

This causes a lower extracellular protein production and may cause autolysis (Kratky and Vinsova, 2011)

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Trypsin was set as digestion enzyme (specific), carbamidomethylation was considered as fixed cysteine modification and N-terminal acetylation and methionine oxidation were considered as variable modifications
