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10.22514/sv.2021.127 [DOI] [Google Scholar] 64.Gonzlez-Flores D, Lpez-Pingarrn L, Castao MY, Gmez M, Rodrguez AB, Garca JJ, Garrido M

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2 Muscle atrophy and cancer cachexia Chronic systemic inflammation, triggered and sustained by cytokines as well as increased oxidative stress, contribute to the pathogenesis of cachexia

In a mouse aging model induced by D-galactose, Polygonatum sibiricum Redout polysaccharide regulates the function of mitochondria-associated membranes (MAMs) by downregulating the expression of key proteins such as IP3R, GRP75, and VDAC1, as well as decreasing the expression of the mitochondrial calcium uniporter (MCU), maintaining intracellular calcium homeostasis (99)

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