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It stimulates Akt, ERK1/2 and P38 MAP kinase leading to Nrf2 phosphorylation and its import into the nucleus [202, 218]

Glob J Med Res

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89 This occurs through hypoxia-mediated suppression of matrix mineralization-related enzymes, as well as reduced expression and activity of alkaline phosphatase

Subcutaneous administration of monosodium L-glutamate to neonatal mice causes cataracts 29