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Your provider might recommend switching to a different contraceptive method, such as non-oral birth control, or suggest using barrier methods (such as condoms) after starting or increasing your dose

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This model is operationally feasible only where the protocol's safety and efficacy requirements can be entirely satisfied through validated remote instruments: ePRO platforms, wearable biosensors, home nursing procedures, telemedicine investigator visits, and direct-to-patient supply chain logistics

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Safety is unknownand potentially problematic

Other orally administered sensitive P-gp substrates (e.g., sirolimus, tacrolimus, digoxin): Increases in exposure may be observed on coadministration with Epidiolex, so therapeutic drug monitoring and dose reduction of other P-gp substrates should be considered when given orally and concurrently with Epidiolex