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(1977) Relationship between the soluble glutathione-dependent A 5 -3- ketosteroid isomerase and the glutathione 5-transferases of the liver, Proc

In this work, by noting that pre-equilibration of ligand-receptor and ternary complex formation occur faster than the receptor internalization and downregulation, we formulate a minimal kinetic model to offer a semi-quantitative yet predictive understanding of the GPCR desensitization and down-regulation
