melanotic macule inside cheek Smokers melanosis . Oral pigmentation seen in heavy smokers . Investigations have shown ability of melanin to bind to noxious substances. . Exposure to polycyclic amines ( Nicotine & benzpyrene) has shown Pigmented (Purple or Brown) Lesions

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PLoS One (2016)

Placement : C purlins are typically installed horizontally along roofs or walls to carry and distribute loads from roof panels, cladding, or mezzanine floors