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While some studies suggest that NAC may reduce exacerbation frequency and enhance lung function in COPD patients, others have not observed significant benefits

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Standardization of time duration was performed in our previous experiments which showed that, 12 h duration (among the tested durations 1 h, 3 h, 6 h, 12 h, 24 h and 48 h) of hypoxia exposure was the optimum time, at which maximum renal damage had occurred 26

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10.1016/j.bbabio.2012.11.005 57 HolmgrenA

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