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However, this effect was reproduced by a novel ER agonist (55)

Progress in the Development of Preventative Drugs for Cisplatin-Induced Hearing Loss: Miniperspective

doi: 10.1208/s12248-025-01018-9 179 ZhangSLiuJOuyangXLiuWWangYZhongJ

Pizzino, G., Irrera, N., Cucinotta, M., Pallio, G., Mannino, F., Arcoraci, V., & Squadrito, F

While a single bout of exercise is suggested to lead to a limited adaptive response, regular exercise appears to gradually increase the level of adaptation by the repeated activation of antioxidant genes and proteins [32]