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Protein turnover releases - N -trimethyllysine, which is hydroxylated by - N -trimethyllysine hydroxylase in a reaction requiring Fe 2+ and ascorbate, producing -hydroxy-- N -trimethyllysine

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Similarly, a study that was conducted in rats to prevent the occurrence of myoclonic jerks and the generalized clonic seizure demonstrated that histidine is the precursor of His

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