glutathione thioesters Model of Glo2 catalysis. The position of the nucleophile-generating Glutathione Precursors by Genestra helps to protect against oxidative stress and supports glutathione formation Thioester - an overview |
Description
This finding explains the clinical paradox that giving antioxidants to healthy patients can lead them to develop more cancers than expected. Glutathione and thioredoxin antioxidant pathways synergise to drive cancer initiation and progression

10.1007/s11064-010-0225-0 42 CourtF

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