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doi: 10.1016/j.neuroscience.2015.07.048

In summary, our results demonstrated that TG2 in cell lysates causes GST aggregate formation through crosslinking activity, which interferes with pulldown experiments and alters fused protein function

Intrinsic disorder and protein function

In PET imaging of patients with traumatic brain injury, an increased [ 11 C] SL25.1188 uptake was observed in the prefrontal and cortical brain regions compared with controls, and this increase showed an inverse correlation with performance on the Trail Making Test, reflecting reduced psychomotor and processing speed 371

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However, risks like allergic reactions, kidney strain, or mild injection-site discomfort may occur, so medical supervision is essential