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For instance, beyond their DHAR activity, fungal and bacterial GHRs characterized so far efficiently reduce glutathionylated (chlorinated) (hydro)quinones with k cat around 10 3 s 1 and k cat / K m up to 10 6 M 1 .s 1 (Table 5) (Huang et al., 2008

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doi: 10.1038/sj.bjc.6604971 296 DingXChenWFanHZhuB

There is a dearth of information in the literature to suggest an ability of ghrelin to sustain elevated food intake in animals or humans upon long-term administration, and it is feasible that downregulation would contribute to a decline in orexigenic effects over time

Symptoms of schizophrenia are associated with elevations in glutamatergic metabolites across several brain regions [367] and oxidative stress [40]

Inhibition of pyruvate carboxylase reverses metformin resistance by activating AMPK in pancreatic cancer