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CAN is characterized by damage to the nerve fibers that innervate the heart and blood vessels, leading to reduced heart rate variability (variability in the time interval between heartbeats) and increased risk of mortality (80)

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1,2,7 However, some authors suggest that the evidence for antidepressant treatment of anxiety disorders remains equivocal

Whether that theoretical advantage translates to clinical benefit remains unproven

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Weeks 8-12 : More significant improvements in deeper wrinkles, continued collagen density increase, improved skin thickness (measured via ultrasound in clinical settings), and sustained reduction in age-related skin laxity