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Similarly, it has also been observed that a certain amount of heme iron contained in diets could increase the growth of Gram-negative Enterobacteria and inhibit the growth of Gram-positive Lactobacilli in the feces of rats, which led to increased CRC risk 57

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Therefore, we do not currently recommend its use

The other isoform, sACE, is widely distributed on the surface of endothelia, neuroepithelia, and immune cell cascade 297