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131 The intraperitoneal injection of 1 10 6 human BM-MSCs into IBD mice resulted in thrombospondin-1 (THBS1)-dependent TGF- activation, the induction of peritoneal IL-10 + Bregs, the downregulation of MPO activity, the reduction in IFN- and TNF- levels, the minimal infiltration of inflammatory cells within the lamina propria, and improvements in weight loss and colon shortening in mice

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To demonstrate the benefits of the alkaline wash step, 19 human monoclonal IgG 1 antibody clones (17 light chain, 2 light chain) were purified from 21 medium batches by the standard method or alkaline wash method with a pH 11.0 buffer

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[DOI] [PMC free article] [PubMed] [Google Scholar] Williams DW, Veenstra M, Gaskill PJ, Morgello S, Calderon TM, Berman JW (2014) Monocytes mediate HIV neuropathogenesis: mechanisms that contribute to HIV associated neurocognitive disorders
