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Description
Although they might differ in location and size, their function are similar

USA 102 , 1187611881 (2005)

The intracellular metabolism of glutamate in -cells involves mitochondrial glutamate dehydrogenase, glutamate decarboxylase (GAD), glutamine synthetase, and the synthesis of glutathione (140)

Therefore, EAAT3 plays a crucial role in neuronal defense against ferroptosis

Their multi-target pharmacology presents a unique opportunity for breakthrough therapies in complex disorders such as AD

Interacts with the dopaminergic system and has demonstrated cytoprotective effects on gastric mucosa, tendons, ligaments, and muscle tissue
