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It has been observed that actin GS-ylation contributes to compromised microfilament organization in FDRA fibroblasts, resulting in impaired cytoskeletal functions [91]

Another PubMed review highlights the regenerative and protective actions of GHK-Cu, including gene regulation relevant to skin repair, wound healing, and cell-protective pathways

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Thus, this study focused on the peri-infarction period, where Klotho protein was administered shortly before and after global ischemia

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