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Further, NICE and the BNF says that if there are neurological symptoms present, then every other day injections are the recommended treatment, so all the points you make about B12 being stored and sufficient are not really relevant

The greatest benefit of this design is that it prevents the needle from slipping off the syringe

Have your doctor monitor your B12 levels to make sure you are getting enough

No comprehensive, long-term human safety studies have been published

Data availability statement The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation

NAD+ metabolism enzyme NNMT in cancer-associated fibroblasts drives tumor progression