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Importantly, recent studies aimed at blocking the metaorganismal TMAO pathway through multiple approaches have confirmed the inhibition of diet-dependent atherosclerosis in animal models, either by targeting the initial microbial formation of TMA from choline through use of a nonlethal small-molecule inhibitor (19), or by targeting the second step in the pathway, the major host gene responsible for converting microbe-generated TMA into TMAO, flavin monooxygenase 3 (20, 21)

232 During aging, intracellular calcium regulation capacity declines, calcium homeostasis is unbalanced

Hadi HA, Tarmizi AI, Khalid KA, Gajdcs M, Aslam A, Jamshed S

However, no CRs were observed in the eight patients who had their initial CAR T-cell infusion fail

Dissecting the non-neuronal cell contribution to parkinson's disease pathogenesis using induced pluripotent stem cells

Lipoic acid (LA), a naturally occurring organosulfur compound, is not only essential for mitochondrial aerobic metabolism but also shows therapeutic potential via certain pharmacological effects (e.g., antioxidative and anti-inflammatory effects)